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==Crystal structure of the second StARkin domain of Lam2 in complex with ergosterol==
==Crystal structure of the second StARkin domain of Lam2 in complex with ergosterol==
<StructureSection load='5ys0' size='340' side='right' caption='[[5ys0]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5ys0' size='340' side='right'caption='[[5ys0]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ys0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YS0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ys0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YS0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ERG:ERGOSTEROL'>ERG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.601&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YSP2, LAM2, LTC4, YDR326C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERG:ERGOSTEROL'>ERG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ys0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ys0 OCA], [http://pdbe.org/5ys0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ys0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ys0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ys0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ys0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ys0 OCA], [https://pdbe.org/5ys0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ys0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ys0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ys0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YSP2_YEAST YSP2_YEAST]] Involved in induction of programmed cell death in response to reactive oxygen species (ROS) (PubMed:16962064). May be involved in sterol transfer between intracellular membranes (PubMed:26001273).<ref>PMID:16962064</ref> <ref>PMID:26001273</ref>
[https://www.uniprot.org/uniprot/YSP2_YEAST YSP2_YEAST] Involved in induction of programmed cell death in response to reactive oxygen species (ROS) (PubMed:16962064). May be involved in sterol transfer between intracellular membranes (PubMed:26001273).<ref>PMID:16962064</ref> <ref>PMID:26001273</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Im, Y J]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Tong, J]]
[[Category: Im YJ]]
[[Category: Ligand binding domain]]
[[Category: Tong J]]
[[Category: Lipid transport]]
[[Category: Sterol]]
[[Category: Transport protein]]
[[Category: Ysp2]]
Retrieved from "https://proteopedia.org/5ys0"