5zhv: Difference between revisions

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<StructureSection load='5zhv' size='340' side='right'caption='[[5zhv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5zhv' size='340' side='right'caption='[[5zhv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5zhv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZHV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZHV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5zhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZHV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv3488 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zhv OCA], [http://pdbe.org/5zhv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zhv RCSB], [http://www.ebi.ac.uk/pdbsum/5zhv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zhv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zhv OCA], [https://pdbe.org/5zhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zhv RCSB], [https://www.ebi.ac.uk/pdbsum/5zhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zhv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDDTR_MYCTU CDDTR_MYCTU] May have transcription regulation and metal-detoxifying functions through which it may enhance intracellular survival of mycobacteria. Binds to its own promoter region and to the Rv1999c promoter region. It displays strong affinity for cadmium ions, but can also bind zinc, manganese and nickel. Expression increases the intracellular survival of recombinant M. smegmatis in murine macrophage cell line and increases its tolerance to cadmium ions.<ref>PMID:30266832</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5zhv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5zhv" style="background-color:#fffaf0;"></div>
==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Arora, A]]
[[Category: Arora A]]
[[Category: Biswal, B K]]
[[Category: Biswal BK]]
[[Category: Meera, K]]
[[Category: Meera K]]
[[Category: Pal, R K]]
[[Category: Pal RK]]
[[Category: Dna binding protein]]
Retrieved from "https://proteopedia.org/5zhv"