6jcn: Difference between revisions

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<StructureSection load='6jcn' size='340' side='right'caption='[[6jcn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6jcn' size='340' side='right'caption='[[6jcn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6jcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JCN FirstGlance]. <br>
<table><tr><td colspan='2'>[[6jcn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JCN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.998&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUS1, YDL193W, D1239 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ditrans,polycis-polyprenyl_diphosphate_synthase_((2E,6E)-farnesyl_diphosphate_specific) Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.87 2.5.1.87] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jcn OCA], [https://pdbe.org/6jcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jcn RCSB], [https://www.ebi.ac.uk/pdbsum/6jcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jcn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jcn OCA], [http://pdbe.org/6jcn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jcn RCSB], [http://www.ebi.ac.uk/pdbsum/6jcn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jcn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UPPS_YEAST UPPS_YEAST]] With SRT1 or RER2, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).<ref>PMID:25066056</ref>
[https://www.uniprot.org/uniprot/UPPS_YEAST UPPS_YEAST] With SRT1 or RER2, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).<ref>PMID:25066056</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chen, C C]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Guo, R T]]
[[Category: Chen C-C]]
[[Category: Ko, T P]]
[[Category: Guo R-T]]
[[Category: Liu, W]]
[[Category: Ko T-P]]
[[Category: Ma, J]]
[[Category: Liu W]]
[[Category: Butterfly]]
[[Category: Ma J]]
[[Category: Cis-prenyl transferase]]
[[Category: Dehydrodolichyl diphosphate synthesis]]
[[Category: Heterodimer]]
[[Category: Human ngbr]]
[[Category: Rossmann-like fold]]
[[Category: Transferase]]
[[Category: Yeast rer2]]