6jfg: Difference between revisions

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<StructureSection load='6jfg' size='340' side='right'caption='[[6jfg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='6jfg' size='340' side='right'caption='[[6jfg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6jfg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JFG FirstGlance]. <br>
<table><tr><td colspan='2'>[[6jfg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JFG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K1U:(3R)-3-benzyl-4-oxo-4-[(2-oxo-2-phenylethyl)sulfanyl]butanoic+acid'>K1U</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K1U:(3R)-3-benzyl-4-oxo-4-[(2-oxo-2-phenylethyl)sulfanyl]butanoic+acid'>K1U</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfg OCA], [http://pdbe.org/6jfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jfg RCSB], [http://www.ebi.ac.uk/pdbsum/6jfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfg OCA], [https://pdbe.org/6jfg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jfg RCSB], [https://www.ebi.ac.uk/pdbsum/6jfg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]  
[https://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Peptide deformylase]]
[[Category: Staphylococcus aureus]]
[[Category: Ho, T H]]
[[Category: Ho TH]]
[[Category: Kang, L W]]
[[Category: Kang LW]]
[[Category: Lee, I H]]
[[Category: Lee IH]]
[[Category: Hydrolase]]

Latest revision as of 10:08, 22 November 2023

K1U bound crystal structure of class II peptide deformylase from methicillin resistant Staphylococcus aureus

6jfg, resolution 2.60Å

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