6kvs: Difference between revisions
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==Staphylococcus aureus FabH with covalent inhibitor Oxa1== | ==Staphylococcus aureus FabH with covalent inhibitor Oxa1== | ||
<StructureSection load='6kvs' size='340' side='right'caption='[[6kvs]]' scene=''> | <StructureSection load='6kvs' size='340' side='right'caption='[[6kvs]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KVS OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6kvs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu3 Staphylococcus aureus subsp. aureus Mu3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KVS FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OAX:4-chloranyl-N-[[cyclopropylmethyl(methanoyl)amino]methyl]benzamide'>OAX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kvs OCA], [https://pdbe.org/6kvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kvs RCSB], [https://www.ebi.ac.uk/pdbsum/6kvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kvs ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/FABH_STAA1 FABH_STAA1] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. | |||
==See Also== | |||
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus subsp. aureus Mu3]] | |||
[[Category: Wang J]] | [[Category: Wang J]] | ||
[[Category: Yuan Y]] | [[Category: Yuan Y]] | ||
