1eci: Difference between revisions
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==ECTATOMIN (WATER SOLUTION, NMR 20 STRUCTURES)== | ==ECTATOMIN (WATER SOLUTION, NMR 20 STRUCTURES)== | ||
<StructureSection load='1eci' size='340' side='right'caption='[[1eci | <StructureSection load='1eci' size='340' side='right'caption='[[1eci]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1eci]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ectatomma_tuberculatum Ectatomma tuberculatum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ECI FirstGlance]. <br> | <table><tr><td colspan='2'>[[1eci]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ectatomma_tuberculatum Ectatomma tuberculatum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ECI FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eci OCA], [https://pdbe.org/1eci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eci RCSB], [https://www.ebi.ac.uk/pdbsum/1eci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eci ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eci OCA], [https://pdbe.org/1eci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eci RCSB], [https://www.ebi.ac.uk/pdbsum/1eci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eci ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TX1AA_ECTTU TX1AA_ECTTU] Algogenic for animals, human and insects (PubMed:7826413). At high concentrations (0.5-1 uM), it acts as a pore-forming protein that forms nonselective cation channels both in cell and artificial membranes (PubMed:7826413). It is weakly selective for cation over anions channel conductance is identical in both directions. At lower concentrations (1-10 nM), this heterodimer inhibits cardiac L-type calcium currents in isolated rat cardiac ventricular myocytes (PubMed:10336635).<ref>PMID:10336635</ref> <ref>PMID:7826413</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Ectatomma tuberculatum]] | [[Category: Ectatomma tuberculatum]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arseniev | [[Category: Arseniev AS]] | ||
[[Category: Grishin | [[Category: Grishin EV]] | ||
[[Category: Nolde | [[Category: Nolde DE]] | ||
[[Category: Pluzhnikov | [[Category: Pluzhnikov KA]] | ||
[[Category: Sobol | [[Category: Sobol AG]] | ||
