2mcv: Difference between revisions

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==Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers==
==Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers==
<StructureSection load='2mcv' size='340' side='right'caption='[[2mcv]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2mcv' size='340' side='right'caption='[[2mcv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mcv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MCV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mcv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Morone_saxatilis Morone saxatilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MCV FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jos|2jos]], [[2ojm|2ojm]], [[2mcu|2mcu]], [[2mcw|2mcw]], [[2mcx|2mcx]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mcv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mcv OCA], [https://pdbe.org/2mcv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mcv RCSB], [https://www.ebi.ac.uk/pdbsum/2mcv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mcv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mcv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mcv OCA], [https://pdbe.org/2mcv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mcv RCSB], [https://www.ebi.ac.uk/pdbsum/2mcv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mcv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MORO_MORSA MORO_MORSA]] Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as against a variety of fungi. Has hemolytic activity. Seems to disrupt the membranes by adopting an alpha helical conformation and forming toroidal pores.<ref>PMID:11713517</ref> <ref>PMID:17253775</ref>
[https://www.uniprot.org/uniprot/MORO_MORSA MORO_MORSA] Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as against a variety of fungi. Has hemolytic activity. Seems to disrupt the membranes by adopting an alpha helical conformation and forming toroidal pores.<ref>PMID:11713517</ref> <ref>PMID:17253775</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cotten, M L]]
[[Category: Morone saxatilis]]
[[Category: Fu, R]]
[[Category: Cotten ML]]
[[Category: Grant, C V]]
[[Category: Fu R]]
[[Category: Hayden, R M]]
[[Category: Grant CV]]
[[Category: Pastor, R W]]
[[Category: Hayden RM]]
[[Category: Perrin, B S]]
[[Category: Pastor RW]]
[[Category: Tian, Y]]
[[Category: Perrin Jr BS]]
[[Category: Amphipathic]]
[[Category: Tian Y]]
[[Category: Anti hiv-1]]
[[Category: Anticancer peptide]]
[[Category: Antimicrobial peptide]]
[[Category: Antimicrobial protein]]
[[Category: Bacterial cell membrane mimic]]
[[Category: Cationic]]
[[Category: Helical]]
[[Category: Histidine rich]]
[[Category: Lipid bilayer]]
Retrieved from "https://proteopedia.org/2mcv"