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==Neurotoxin II from snake venom Naja Oxiana in solution==
==Neurotoxin II from snake venom Naja Oxiana in solution==
<StructureSection load='2mj4' size='340' side='right'caption='[[2mj4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mj4' size='340' side='right'caption='[[2mj4]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mj4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Central_asian_cobra Central asian cobra]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJ4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mj4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJ4 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nor|1nor]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mj4 OCA], [https://pdbe.org/2mj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mj4 RCSB], [https://www.ebi.ac.uk/pdbsum/2mj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mj4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mj4 OCA], [https://pdbe.org/2mj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mj4 RCSB], [https://www.ebi.ac.uk/pdbsum/2mj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mj4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NXS1_NAJOX NXS1_NAJOX]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor.  
[https://www.uniprot.org/uniprot/3S11_NAJOX 3S11_NAJOX] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Central asian cobra]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arseniev, A S]]
[[Category: Naja oxiana]]
[[Category: Bocharov, E V]]
[[Category: Arseniev AS]]
[[Category: Lesovoy, D M]]
[[Category: Bocharov EV]]
[[Category: Lyukmanova, E N]]
[[Category: Lesovoy DM]]
[[Category: Nolde, S B]]
[[Category: Lyukmanova EN]]
[[Category: 13c relaxation]]
[[Category: Nolde SB]]
[[Category: Molecular dynamic]]
[[Category: Molecular mechanics force field]]
[[Category: Optimization]]
[[Category: Side chain dynamic]]
[[Category: Toxin]]

Revision as of 11:56, 22 November 2023

Neurotoxin II from snake venom Naja Oxiana in solution

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