8pvd: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The~~ entry ~~8pvd~~ is ~~ON HOLD until Paper Publication~~

==Structure of catalase determined by cryoEM at 100 keV==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8pvd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PVD OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8PVD FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8pvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pvd OCA], [https://pdbe.org/8pvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pvd RCSB], [https://www.ebi.ac.uk/pdbsum/8pvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pvd ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Defects in CAT are the cause of acatalasemia (ACATLAS) [MIM:[https://omim.org/entry/614097 614097]. A metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.<ref>PMID:2308162</ref>

== Function ==

[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.<ref>PMID:7882369</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Cannone G]]

[[Category: Chen S]]

[[Category: Dalby J]]

[[Category: Dickerson JL]]

[[Category: El-Gomati MM]]

[[Category: Gittins O]]

[[Category: Henderson R]]

[[Category: Hutchings KA]]

[[Category: Lee Y]]

[[Category: McMullan G]]

[[Category: Meffert M]]

[[Category: Mihaylov D]]

[[Category: Naydenova K]]

[[Category: Peet MJ]]

[[Category: Russo CJ]]

[[Category: Schulze-Briese C]]

[[Category: Sobhy M]]

[[Category: Wells T]]

[[Category: Wilson H]]

[[Category: Yamashita K]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8pvd is ON HOLD  until Paper Publication
+==Structure of catalase determined by cryoEM at 100 keV==
+<StructureSection load='8pvd' size='340' side='right'caption='[[8pvd]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8pvd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PVD FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pvd OCA], [https://pdbe.org/8pvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pvd RCSB], [https://www.ebi.ac.uk/pdbsum/8pvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pvd ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Defects in CAT are the cause of acatalasemia (ACATLAS) [MIM:[https://omim.org/entry/614097 614097]. A metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.<ref>PMID:2308162</ref>
+== Function ==
+[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.<ref>PMID:7882369</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Cannone G]]
+[[Category: Chen S]]
+[[Category: Dalby J]]
+[[Category: Dickerson JL]]
+[[Category: El-Gomati MM]]
+[[Category: Gittins O]]
+[[Category: Henderson R]]
+[[Category: Hutchings KA]]
+[[Category: Lee Y]]
+[[Category: McMullan G]]
+[[Category: Meffert M]]
+[[Category: Mihaylov D]]
+[[Category: Naydenova K]]
+[[Category: Peet MJ]]
+[[Category: Russo CJ]]
+[[Category: Schulze-Briese C]]
+[[Category: Sobhy M]]
+[[Category: Wells T]]
+[[Category: Wilson H]]
+[[Category: Yamashita K]]