6m36: Difference between revisions
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The | ==The crystal structure of B. subtilis RsbV/RsbW complex in the monoclinic crystal form== | ||
<StructureSection load='6m36' size='340' side='right'caption='[[6m36]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6m36]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M36 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m36 OCA], [https://pdbe.org/6m36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m36 RCSB], [https://www.ebi.ac.uk/pdbsum/6m36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m36 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RSBW_BACSU RSBW_BACSU] Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).<ref>PMID:1592822</ref> <ref>PMID:8144446</ref> <ref>PMID:8468294</ref> | |||
==See Also== | |||
*[[Anti-sigma factor antagonist 3D structures|Anti-sigma factor antagonist 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Kim | __TOC__ | ||
[[Category: Kwon | </StructureSection> | ||
[[Category: Pathak | [[Category: Bacillus subtilis subsp. subtilis str. 168]] | ||
[[Category: Large Structures]] | |||
[[Category: Kim DY]] | |||
[[Category: Kwon E]] | |||
[[Category: Pathak D]] | |||