7cbn: Difference between revisions

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==Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7CBN FirstGlance].

<table><tr><td colspan='2'>[[7cbn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Akkermansia_muciniphila_ATCC_BAA-835 Akkermansia muciniphila ATCC BAA-835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7CBN FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=7cbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cbn OCA], [~~http~~://pdbe.org/7cbn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7cbn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7cbn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7cbn ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7cbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cbn OCA], [https://pdbe.org/7cbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cbn RCSB], [https://www.ebi.ac.uk/pdbsum/7cbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cbn ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/H0868_AKKM8 H0868_AKKM8] Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes chromogenic substrates pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lesser extent, but not pNP-beta-glucose or pNP-beta-galactose (PubMed:32819592).<ref>PMID:32819592</ref>

==See Also==

*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]

== References ==

__TOC__

</StructureSection>

[[Category: Akkermansia muciniphila ATCC BAA-835]]

[[Category: Large Structures]]

[[Category: Wang M]]

[[Category: Xu W]]

[[Category: Zhang M]]

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@@ Line 1: / Line 1: @@
 ==Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila==
-<StructureSection load='7cbn' size='340' side='right'caption='[[7cbn]]' scene=''>
+<StructureSection load='7cbn' size='340' side='right'caption='[[7cbn]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CBN FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7cbn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Akkermansia_muciniphila_ATCC_BAA-835 Akkermansia muciniphila ATCC BAA-835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CBN FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cbn OCA], [http://pdbe.org/7cbn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cbn RCSB], [http://www.ebi.ac.uk/pdbsum/7cbn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cbn ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cbn OCA], [https://pdbe.org/7cbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cbn RCSB], [https://www.ebi.ac.uk/pdbsum/7cbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cbn ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/H0868_AKKM8 H0868_AKKM8] Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes chromogenic substrates pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lesser extent, but not pNP-beta-glucose or pNP-beta-galactose (PubMed:32819592).<ref>PMID:32819592</ref>
+==See Also==
+*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Akkermansia muciniphila ATCC BAA-835]]
 [[Category: Large Structures]]
 [[Category: Wang M]]
 [[Category: Xu W]]
 [[Category: Zhang M]]