7ck9: Difference between revisions
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==Crystal structure of Doxorubicin loaded human ferritin heavy chain== | ==Crystal structure of Doxorubicin loaded human ferritin heavy chain== | ||
<StructureSection load='7ck9' size='340' side='right'caption='[[7ck9]]' scene=''> | <StructureSection load='7ck9' size='340' side='right'caption='[[7ck9]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7ck9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck9 OCA], [https://pdbe.org/7ck9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck9 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck9 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.602Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck9 OCA], [https://pdbe.org/7ck9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck9 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
==See Also== | |||
*[[Ferritin 3D structures|Ferritin 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen X]] | [[Category: Chen X]] | ||
Latest revision as of 16:09, 29 November 2023
Crystal structure of Doxorubicin loaded human ferritin heavy chain
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