1mxn: Difference between revisions
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==Solution structure of alpha-conotoxin AuIB== | ==Solution structure of alpha-conotoxin AuIB== | ||
<StructureSection load='1mxn' size='340' side='right'caption='[[1mxn | <StructureSection load='1mxn' size='340' side='right'caption='[[1mxn]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mxn]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MXN FirstGlance]. <br> | <table><tr><td colspan='2'>[[1mxn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_aulicus Conus aulicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MXN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mxn OCA], [https://pdbe.org/1mxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mxn RCSB], [https://www.ebi.ac.uk/pdbsum/1mxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mxn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mxn OCA], [https://pdbe.org/1mxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mxn RCSB], [https://www.ebi.ac.uk/pdbsum/1mxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mxn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CA1B_CONAL CA1B_CONAL] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian nAChR alpha-3/beta-4 subunits.<ref>PMID:9786965</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 23: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Conus aulicus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Adams | [[Category: Adams DJ]] | ||
[[Category: Alewood | [[Category: Alewood PF]] | ||
[[Category: Bansal | [[Category: Bansal PS]] | ||
[[Category: Craik | [[Category: Craik DJ]] | ||
[[Category: Dutton | [[Category: Dutton JL]] | ||
[[Category: Hogg | [[Category: Hogg RC]] | ||
Latest revision as of 18:51, 29 November 2023
Solution structure of alpha-conotoxin AuIB
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