5o1m: Difference between revisions

<table><tr><td colspan='2'>[[5o1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._K30 Streptomyces sp. K30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O1M FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o1m OCA], [https://pdbe.org/5o1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o1m RCSB], [https://www.ebi.ac.uk/pdbsum/5o1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o1m ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/LCP_STRK3 LCP_STRK3] Involved in the initial step of rubber degradation (PubMed:22950008, PubMed:15638519, PubMed:18606806). Catalyzes the oxidative C-C cleavage of poly(cis-1,4-isoprene) in synthetic as well as in natural rubber by the addition of oxygen (O2) to the double bonds, leading to a mixture of oligonucleotide-isoprenoids with terminal keto and aldehyde groups (endo-type cleavage) (PubMed:25819959, PubMed:24907333). The cleavage products are of different lengths, ranging from C20 (four isoprene units) to higher oligo-isoprenoids (PubMed:24907333). Is not able to cleave low-molecular-weight substrate analogs with isoprenoid structure such as squalene (1,4-trans-isoprenoid), carotenoids, or alpha-tocopherol (PubMed:24907333).<ref>PMID:15638519</ref> <ref>PMID:18606806</ref> <ref>PMID:22950008</ref> <ref>PMID:24907333</ref> <ref>PMID:25819959</ref>  

[[Category: Birke J]]

[[Category: Brausemann A]]

[[Category: Einsle O]]

[[Category: Ilcu L]]

[[Category: Jendrossek D]]

[[Category: Roether W]]