5o5o: Difference between revisions

<table><tr><td colspan='2'>[[5o5o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O5O FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.404&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o5o OCA], [https://pdbe.org/5o5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o5o RCSB], [https://www.ebi.ac.uk/pdbsum/5o5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o5o ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RAPZ_ECOLI RAPZ_ECOLI] Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS (PubMed:17824929, PubMed:23475961). Displays ATPase and GTPase activities in vitro. Can also hydrolyze pNPP (PubMed:19074378).<ref>PMID:17824929</ref> <ref>PMID:19074378</ref> <ref>PMID:23475961</ref>  

[[Category: Durica-Mitic S]]

[[Category: Ficner R]]

[[Category: Gonzalez GM]]

[[Category: Gorke B]]

[[Category: Hardwick SW]]

[[Category: Luisi BF]]

[[Category: Moncrieffe M]]

[[Category: Neumann P]]

[[Category: Resch M]]