Acetazolamide: Difference between revisions
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Acetazolamide, sold under the trade name Diamox among others, is a medication used to treat glaucoma, epilepsy, acute mountain sickness, periodic paralysis, idiopathic intracranial hypertension (raised brain pressure of unclear cause), heart failure and to alkalinize urine.<ref name="a2">[https://www.drugs.com/monograph/acetazolamide.html "Acetazolamide".] The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.</ref><ref name="a3">PMID:28758206</ref> See also [https://en.wikipedia.org/wiki/Acetazolamide Acetazolamide]. | Acetazolamide, sold under the trade name Diamox among others, is a medication used to treat glaucoma, epilepsy, acute mountain sickness, periodic paralysis, idiopathic intracranial hypertension (raised brain pressure of unclear cause), heart failure and to alkalinize urine.<ref name="a2">[https://www.drugs.com/monograph/acetazolamide.html "Acetazolamide".] The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.</ref><ref name="a3">PMID:28758206</ref> See also [https://en.wikipedia.org/wiki/Acetazolamide Acetazolamide]. | ||
Acetazolamide is a carbonic anhydrase inhibitor, hence causing the accumulation of carbonic acid.[12] Carbonic anhydrase is an enzyme found in red blood cells and many other tissues that catalyses the following reaction:[26] | Acetazolamide is a carbonic anhydrase inhibitor, hence causing the accumulation of carbonic acid.<ref name="a12">Brayfield A, ed. (7 January 2014). [https://www.medicinescomplete.com/log-in/#/content/martindale/2301-x "Acetazolamide".] Martindale: The Complete Drug Reference. Pharmaceutical Press. Retrieved 10 April 2014.</ref>[12] Carbonic anhydrase is an enzyme found in red blood cells and many other tissues that catalyses the following reaction:[26] | ||
H2CO3 ⇌ H2O + CO2 | H2CO3 ⇌ H2O + CO2 | ||
