1ea5: Difference between revisions

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<StructureSection load='1ea5' size='340' side='right'caption='[[1ea5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1ea5' size='340' side='right'caption='[[1ea5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ea5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EA5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1EA5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ea5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EA5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1amn|1amn]], [[1ax9|1ax9]], [[1cfj|1cfj]], [[1dx6|1dx6]], [[1e3q|1e3q]], [[1e66|1e66]], [[1eea|1eea]], [[1eve|1eve]], [[1fss|1fss]], [[1oce|1oce]], [[1qid|1qid]], [[1qie|1qie]], [[1qif|1qif]], [[1qig|1qig]], [[1qih|1qih]], [[1qii|1qii]], [[1qij|1qij]], [[1qik|1qik]], [[1qim|1qim]], [[1qti|1qti]], [[1som|1som]], [[1vot|1vot]], [[1vxo|1vxo]], [[1vxr|1vxr]], [[2ace|2ace]], [[2ack|2ack]], [[2dfp|2dfp]], [[3ace|3ace]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ea5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ea5 OCA], [https://pdbe.org/1ea5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ea5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ea5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ea5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ea5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ea5 OCA], [http://pdbe.org/1ea5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ea5 RCSB], [http://www.ebi.ac.uk/pdbsum/1ea5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ea5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.  
[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
*[[Acetylcholinesterase: Treatment of Alzheimer's disease|Acetylcholinesterase: Treatment of Alzheimer's disease]]
*[[Aricept Complexed with Acetylcholinesterase|Aricept Complexed with Acetylcholinesterase]]
*[[Aricept Complexed with Acetylcholinesterase (Arabic)|Aricept Complexed with Acetylcholinesterase (Arabic)]]
*[[Aricept Complexed with Acetylcholinesterase (Catalan)|Aricept Complexed with Acetylcholinesterase (Catalan)]]
*[[Aricept Complexed with Acetylcholinesterase (Chinese)|Aricept Complexed with Acetylcholinesterase (Chinese)]]
*[[Aricept Complexed with Acetylcholinesterase (Czech)|Aricept Complexed with Acetylcholinesterase (Czech)]]
*[[Aricept Complexed with Acetylcholinesterase (French)|Aricept Complexed with Acetylcholinesterase (French)]]
*[[Aricept Complexed with Acetylcholinesterase (German)|Aricept Complexed with Acetylcholinesterase (German)]]
*[[Aricept Complexed with Acetylcholinesterase (Hebrew)|Aricept Complexed with Acetylcholinesterase (Hebrew)]]
*[[Aricept Complexed with Acetylcholinesterase (Hindi)|Aricept Complexed with Acetylcholinesterase (Hindi)]]
*[[Aricept Complexed with Acetylcholinesterase (Italian)|Aricept Complexed with Acetylcholinesterase (Italian)]]
*[[Aricept Complexed with Acetylcholinesterase (Russian)|Aricept Complexed with Acetylcholinesterase (Russian)]]
*[[Aricept Complexed with Acetylcholinesterase (Slovak)|Aricept Complexed with Acetylcholinesterase (Slovak)]]
*[[Aricept Complexed with Acetylcholinesterase (Spanish)|Aricept Complexed with Acetylcholinesterase (Spanish)]]
*[[Aricept Complexed with Acetylcholinesterase (Turkish)|Aricept Complexed with Acetylcholinesterase (Turkish)]]
*[[Aricept Complexed with Acetylcholinesterase (Vietnamese)|Aricept Complexed with Acetylcholinesterase (Vietnamese)]]
*[[Journal:Neuropharmacology:1|Journal:Neuropharmacology:1]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acetylcholinesterase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Torpedo californica]]
[[Category: Tetronarce californica]]
[[Category: Harel, M]]
[[Category: Harel M]]
[[Category: Silman, I]]
[[Category: Silman I]]
[[Category: Sussman, J L]]
[[Category: Sussman JL]]
[[Category: Weik, M]]
[[Category: Weik M]]
[[Category: Alpha/beta hydrolase]]
[[Category: Catalytic triad]]
[[Category: Hydrolase]]
[[Category: Neurotransmitter cleavage]]
[[Category: Serine hydrolase]]