1h0a: Difference between revisions

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<StructureSection load='1h0a' size='340' side='right'caption='[[1h0a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1h0a' size='340' side='right'caption='[[1h0a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1h0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0A FirstGlance]. <br>
<table><tr><td colspan='2'>[[1h0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1edu|1edu]], [[1eyh|1eyh]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0a OCA], [https://pdbe.org/1h0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0a RCSB], [https://www.ebi.ac.uk/pdbsum/1h0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0a OCA], [https://pdbe.org/1h0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0a RCSB], [https://www.ebi.ac.uk/pdbsum/1h0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EPN1_RAT EPN1_RAT]] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis.<ref>PMID:9723620</ref> <ref>PMID:11161217</ref> <ref>PMID:12353027</ref>
[https://www.uniprot.org/uniprot/EPN1_RAT EPN1_RAT] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis.<ref>PMID:9723620</ref> <ref>PMID:11161217</ref> <ref>PMID:12353027</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Evans, P R]]
[[Category: Rattus norvegicus]]
[[Category: Ford, M G.J]]
[[Category: Evans PR]]
[[Category: McMahon, H T]]
[[Category: Ford MGJ]]
[[Category: Alpha-alpha superhelix]]
[[Category: McMahon HT]]
[[Category: Clathrin]]
[[Category: Coated vesicle]]
[[Category: Endocytosis]]
[[Category: Enth]]
[[Category: Epsin]]
[[Category: Triskelion]]
Retrieved from "https://proteopedia.org/1h0a"