1h0o: Difference between revisions

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<StructureSection load='1h0o' size='340' side='right'caption='[[1h0o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1h0o' size='340' side='right'caption='[[1h0o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1h0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0O FirstGlance]. <br>
<table><tr><td colspan='2'>[[1h0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aft|1aft]], [[1h0n|1h0n]], [[1xsm|1xsm]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0o OCA], [https://pdbe.org/1h0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0o RCSB], [https://www.ebi.ac.uk/pdbsum/1h0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0o OCA], [https://pdbe.org/1h0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0o RCSB], [https://www.ebi.ac.uk/pdbsum/1h0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RIR2_MOUSE RIR2_MOUSE]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling (By similarity).  
[https://www.uniprot.org/uniprot/RIR2_MOUSE RIR2_MOUSE] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Andersson KK]]
[[Category: Andersson, K K]]
[[Category: Karlsen S]]
[[Category: Karlsen, S]]
[[Category: Strand KR]]
[[Category: Strand, K R]]
[[Category: Dinuclear metal-cluster]]
[[Category: Oxidoreductase]]
[[Category: Ribonucleotide reductase]]
Retrieved from "https://proteopedia.org/1h0o"