2boo: Difference between revisions

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<StructureSection load='2boo' size='340' side='right'caption='[[2boo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2boo' size='340' side='right'caption='[[2boo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2boo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BOO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2boo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BOO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Uridine_nucleosidase Uridine nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.3 3.2.2.3] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2boo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2boo OCA], [https://pdbe.org/2boo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2boo RCSB], [https://www.ebi.ac.uk/pdbsum/2boo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2boo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2boo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2boo OCA], [https://pdbe.org/2boo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2boo RCSB], [https://www.ebi.ac.uk/pdbsum/2boo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2boo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UNG_DEIRA UNG_DEIRA]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).  
[https://www.uniprot.org/uniprot/UNG_DEIRA UNG_DEIRA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Deira]]
[[Category: Deinococcus radiodurans R1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Uridine nucleosidase]]
[[Category: Leiros I]]
[[Category: Leiros, I]]
[[Category: McSweeney S]]
[[Category: McSweeney, S]]
[[Category: Moe E]]
[[Category: Moe, E]]
[[Category: Smalas AO]]
[[Category: Smalas, A O]]
[[Category: Base excision repair]]
[[Category: Dna damage]]
[[Category: Dna repair]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Radiation resistance]]

Latest revision as of 13:50, 13 December 2023

The crystal structure of Uracil-DNA N-Glycosylase (UNG) from Deinococcus radiodurans.

2boo, resolution 1.80Å

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