2byk: Difference between revisions
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<StructureSection load='2byk' size='340' side='right'caption='[[2byk]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2byk' size='340' side='right'caption='[[2byk]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2byk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2byk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BYK FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2byk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2byk OCA], [https://pdbe.org/2byk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2byk RCSB], [https://www.ebi.ac.uk/pdbsum/2byk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2byk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2byk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2byk OCA], [https://pdbe.org/2byk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2byk RCSB], [https://www.ebi.ac.uk/pdbsum/2byk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2byk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DPOE3_DROME DPOE3_DROME] Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Histone-like protein which promotes nucleosome sliding of ATP-dependent nucleosome remodeling complexes (PubMed:10856248, PubMed:11447119, PubMed:18327268). Part of the chromatin-accessibility complex (CHRAC) which uses energy/ATP to increase the general accessibility of DNA in chromatin (PubMed:10856248, PubMed:11447119). As an heterodimer with Chrac-16, binds DNA and facilitates nucleosome sliding by Acf (PubMed:16260604). Has a role in DNA damage response by preventing cid mislocalization to chromatin (PubMed:24703848).[UniProtKB:Q04603][UniProtKB:Q9NRF9]<ref>PMID:10856248</ref> <ref>PMID:11447119</ref> <ref>PMID:16260604</ref> <ref>PMID:18327268</ref> <ref>PMID:24703848</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Becker | [[Category: Becker PB]] | ||
[[Category: Eberharter | [[Category: Eberharter A]] | ||
[[Category: Fernandez-Tornero | [[Category: Fernandez-Tornero C]] | ||
[[Category: Grune | [[Category: Grune T]] | ||
[[Category: Hartlepp | [[Category: Hartlepp KF]] | ||
[[Category: Muller | [[Category: Muller CW]] | ||
