2c3t: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='2c3t' size='340' side='right'caption='[[2c3t]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2c3t' size='340' side='right'caption='[[2c3t]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c3t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2c3t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C3T FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c3t OCA], [https://pdbe.org/2c3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c3t RCSB], [https://www.ebi.ac.uk/pdbsum/2c3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c3t ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c3t OCA], [https://pdbe.org/2c3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c3t RCSB], [https://www.ebi.ac.uk/pdbsum/2c3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c3t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GSTT1_HUMAN GSTT1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.<ref>PMID:16298388</ref> <ref>PMID:20097269</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 34: | Line 35: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kleywegt | [[Category: Kleywegt GJ]] | ||
[[Category: Larsson | [[Category: Larsson A-K]] | ||
[[Category: Mannervik | [[Category: Mannervik B]] | ||
[[Category: Olin | [[Category: Olin B]] | ||
[[Category: Shokeer | [[Category: Shokeer A]] | ||
[[Category: Tars | [[Category: Tars K]] | ||