2c4j: Difference between revisions

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<StructureSection load='2c4j' size='340' side='right'caption='[[2c4j]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='2c4j' size='340' side='right'caption='[[2c4j]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c4j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C4J FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c4j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C4J FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSO:L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE'>GSO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hna|1hna]], [[1hnb|1hnb]], [[1hnc|1hnc]], [[1xw5|1xw5]], [[1ykc|1ykc]], [[2ab6|2ab6]], [[2gtu|2gtu]], [[3gtu|3gtu]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSO:L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE'>GSO</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4j OCA], [https://pdbe.org/2c4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c4j RCSB], [https://www.ebi.ac.uk/pdbsum/2c4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c4j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4j OCA], [https://pdbe.org/2c4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c4j RCSB], [https://www.ebi.ac.uk/pdbsum/2c4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c4j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTM2_HUMAN GSTM2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16549767</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Andersson, M]]
[[Category: Andersson M]]
[[Category: Ivarsson, Y]]
[[Category: Ivarsson Y]]
[[Category: Mannervik, B]]
[[Category: Mannervik B]]
[[Category: Olin, B]]
[[Category: Olin B]]
[[Category: Tars, K]]
[[Category: Tars K]]
[[Category: Glutathione]]
[[Category: M2-2]]
[[Category: Multigene family]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/2c4j"