2cjz: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
Line 3: Line 3:
<StructureSection load='2cjz' size='340' side='right'caption='[[2cjz]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2cjz' size='340' side='right'caption='[[2cjz]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cjz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cjz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bij|2bij]], [[2bv5|2bv5]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjz OCA], [https://pdbe.org/2cjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cjz RCSB], [https://www.ebi.ac.uk/pdbsum/2cjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cjz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjz OCA], [https://pdbe.org/2cjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cjz RCSB], [https://www.ebi.ac.uk/pdbsum/2cjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cjz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTN5_HUMAN PTN5_HUMAN] May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.<ref>PMID:21777200</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Arrowsmith C]]
[[Category: Arrowsmith, C]]
[[Category: Barr AJ]]
[[Category: Barr, A J]]
[[Category: Burgess N]]
[[Category: Burgess, N]]
[[Category: Debreczeni JE]]
[[Category: Debreczeni, J E]]
[[Category: Edwards A]]
[[Category: Delft, F von]]
[[Category: Eswaran J]]
[[Category: Edwards, A]]
[[Category: Gileadi O]]
[[Category: Eswaran, J]]
[[Category: Knapp S]]
[[Category: Gileadi, O]]
[[Category: Savitsky P]]
[[Category: Knapp, S]]
[[Category: Smee C]]
[[Category: Savitsky, P]]
[[Category: Sundstrom M]]
[[Category: Smee, C]]
[[Category: Weigelt J]]
[[Category: Sundstrom, M]]
[[Category: Von Delft F]]
[[Category: Weigelt, J]]
[[Category: Hydrolase]]
[[Category: Phosphatase]]
[[Category: Protein phosphatase]]
[[Category: Ptpn5]]
[[Category: Step]]