2iw0: Difference between revisions

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<StructureSection load='2iw0' size='340' side='right'caption='[[2iw0]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
<StructureSection load='2iw0' size='340' side='right'caption='[[2iw0]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iw0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bean_anthracnose_fungus Bean anthracnose fungus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IW0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iw0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Colletotrichum_lindemuthianum Colletotrichum lindemuthianum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IW0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chitin_deacetylase Chitin deacetylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.41 3.5.1.41] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iw0 OCA], [https://pdbe.org/2iw0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iw0 RCSB], [https://www.ebi.ac.uk/pdbsum/2iw0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iw0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iw0 OCA], [https://pdbe.org/2iw0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iw0 RCSB], [https://www.ebi.ac.uk/pdbsum/2iw0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iw0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDA_COLLN CDA_COLLN] Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine polymers in chitin to form chitosan and acetate (PubMed:15555935, PubMed:7592838, PubMed:8987657, PubMed:9373940, PubMed:16232493, PubMed:16878976). May play a role in evasion of the host immune response; plant chitinases liberate chitin molecules from the fungal cell wall which act as elicitors of the plant immune response, deacetylation of the liberated chitin neutralizes elicitor activity (PubMed:8987657, PubMed:10913295).<ref>PMID:15555935</ref> <ref>PMID:16232493</ref> <ref>PMID:16878976</ref> <ref>PMID:7592838</ref> <ref>PMID:8987657</ref> <ref>PMID:9373940</ref> <ref>PMID:10913295</ref> <ref>PMID:8987657</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bean anthracnose fungus]]
[[Category: Colletotrichum lindemuthianum]]
[[Category: Chitin deacetylase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aalten, D M.F van]]
[[Category: Blair DE]]
[[Category: Blair, D E]]
[[Category: Hekmat O]]
[[Category: Hekmat, O]]
[[Category: Schuttelkopf AW]]
[[Category: Schuttelkopf, A W]]
[[Category: Shrestha B]]
[[Category: Shrestha, B]]
[[Category: Tokuyasu K]]
[[Category: Tokuyasu, K]]
[[Category: Withers SG]]
[[Category: Withers, S G]]
[[Category: Van Aalten DMF]]
[[Category: Chitin de-n-acetylase]]
[[Category: Family 4 carbohydrate esterase]]
[[Category: Hydrolase]]