2ix2: Difference between revisions

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<StructureSection load='2ix2' size='340' side='right'caption='[[2ix2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2ix2' size='340' side='right'caption='[[2ix2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ix2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ix2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX2 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2izo|2izo]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix2 OCA], [https://pdbe.org/2ix2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix2 OCA], [https://pdbe.org/2ix2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PCNA2_SULSO PCNA2_SULSO]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. [[https://www.uniprot.org/uniprot/PCNA3_SULSO PCNA3_SULSO]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication (By similarity).  
[https://www.uniprot.org/uniprot/PCNA1_SACS2 PCNA1_SACS2] One of the sliding clamp subunits that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. Heterotrimer stimulates the Holliday junction resolvase Hjc. DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.<ref>PMID:12535540</ref> <ref>PMID:17011573</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharolobus solfataricus]]
[[Category: Saccharolobus solfataricus]]
[[Category: Large Structures]]
[[Category: Carter L]]
[[Category: Carter, L]]
[[Category: Johnson K]]
[[Category: Johnson, K]]
[[Category: Liu H]]
[[Category: Liu, H]]
[[Category: McMahon SA]]
[[Category: McMahon, S A]]
[[Category: Naismith JH]]
[[Category: Naismith, J H]]
[[Category: Oke M]]
[[Category: Oke, M]]
[[Category: Taylor GL]]
[[Category: Taylor, G L]]
[[Category: White MF]]
[[Category: White, M F]]
[[Category: Williams GJ]]
[[Category: Williams, G J]]
[[Category: Dna replication]]
[[Category: Dna-binding]]
[[Category: Pcna]]
[[Category: Replication]]
[[Category: Sulfolobus sulfataricus]]
Retrieved from "https://proteopedia.org/2ix2"