2j8s: Difference between revisions

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<StructureSection load='2j8s' size='340' side='right'caption='[[2j8s]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
<StructureSection load='2j8s' size='340' side='right'caption='[[2j8s]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2j8s]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli] and [https://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J8S FirstGlance]. <br>
<table><tr><td colspan='2'>[[2j8s]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J8S FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iwg|1iwg]], [[1oy6|1oy6]], [[1oy8|1oy8]], [[1oy9|1oy9]], [[1oyd|1oyd]], [[1oye|1oye]], [[1t9t|1t9t]], [[1t9u|1t9u]], [[1t9v|1t9v]], [[1t9w|1t9w]], [[1t9x|1t9x]], [[1t9y|1t9y]], [[2gif|2gif]], [[2hrt|2hrt]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8s OCA], [https://pdbe.org/2j8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j8s RCSB], [https://www.ebi.ac.uk/pdbsum/2j8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j8s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8s OCA], [https://pdbe.org/2j8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j8s RCSB], [https://www.ebi.ac.uk/pdbsum/2j8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j8s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Synthetic construct sequences]]
[[Category: Synthetic construct]]
[[Category: Amstutz, P]]
[[Category: Amstutz P]]
[[Category: Briand, C]]
[[Category: Briand C]]
[[Category: Gruetter, M G]]
[[Category: Gruetter MG]]
[[Category: Sennhauser, G]]
[[Category: Sennhauser G]]
[[Category: Storchenegger, O]]
[[Category: Storchenegger O]]
[[Category: Antibiotic resistance]]
[[Category: Antibiotic resistance-inhibitor complex]]
[[Category: Co-crystallization]]
[[Category: Designed ankyrin repeat protein]]
[[Category: Drug-efflux pump]]
[[Category: Inhibitor]]
[[Category: Inner membrane]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Membrane protein-complex]]
[[Category: Multidrug resistance protein]]
[[Category: Protein complex]]
[[Category: Rnd]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/2j8s"