2v53: Difference between revisions
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<StructureSection load='2v53' size='340' side='right'caption='[[2v53]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='2v53' size='340' side='right'caption='[[2v53]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2v53]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2v53]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V53 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v53 OCA], [https://pdbe.org/2v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v53 RCSB], [https://www.ebi.ac.uk/pdbsum/2v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v53 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v53 OCA], [https://pdbe.org/2v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v53 RCSB], [https://www.ebi.ac.uk/pdbsum/2v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v53 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SPRC_HUMAN SPRC_HUMAN] Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bachinger | [[Category: Bachinger HP]] | ||
[[Category: Farndale | [[Category: Farndale RW]] | ||
[[Category: Giudici | [[Category: Giudici C]] | ||
[[Category: Hohenester | [[Category: Hohenester E]] | ||
[[Category: Sasaki | [[Category: Sasaki T]] | ||
