2we6: Difference between revisions

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<StructureSection load='2we6' size='340' side='right'caption='[[2we6]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
<StructureSection load='2we6' size='340' side='right'caption='[[2we6]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2we6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WE6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2we6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WE6 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wdt|2wdt]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2we6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2we6 OCA], [https://pdbe.org/2we6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2we6 RCSB], [https://www.ebi.ac.uk/pdbsum/2we6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2we6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2we6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2we6 OCA], [https://pdbe.org/2we6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2we6 RCSB], [https://www.ebi.ac.uk/pdbsum/2we6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2we6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UCHL3_PLAF7 UCHL3_PLAF7] Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8 (PubMed:17371404, PubMed:31658303, PubMed:20042598). Essential for parasite blood stage survival (PubMed:20042598).<ref>PMID:17371404</ref> <ref>PMID:20042598</ref> <ref>PMID:31658303</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Plafa]]
[[Category: Plasmodium falciparum]]
[[Category: Ubiquitinyl hydrolase 1]]
[[Category: Artavanis-Tsakonas K]]
[[Category: Artavanis-Tsakonas, K]]
[[Category: Gaudet R]]
[[Category: Gaudet, R]]
[[Category: Ploegh HL]]
[[Category: Ploegh, H L]]
[[Category: Weihofen WA]]
[[Category: Weihofen, W A]]
[[Category: Cystein proteinase]]
[[Category: Deneddylating enzyme]]
[[Category: Deubiquitinating enzyme]]
[[Category: Hydrolase]]
[[Category: Peptidase_c12]]
[[Category: Ubiquitin isopeptidase]]
[[Category: Uch-l superfamily]]
Retrieved from "https://proteopedia.org/2we6"