2wk1: Difference between revisions
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<StructureSection load='2wk1' size='340' side='right'caption='[[2wk1]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='2wk1' size='340' side='right'caption='[[2wk1]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wk1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WK1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wk1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinoalloteichus_caeruleus Actinoalloteichus caeruleus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WK1 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wk1 OCA], [https://pdbe.org/2wk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wk1 RCSB], [https://www.ebi.ac.uk/pdbsum/2wk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wk1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wk1 OCA], [https://pdbe.org/2wk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wk1 RCSB], [https://www.ebi.ac.uk/pdbsum/2wk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wk1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NOVP_STRNV NOVP_STRNV] S-adenosyl-L-methionine-dependent O-methyltransferase that methylates at 4-OH of the noviose moiety, the penultimate step in the novobiocin biosynthesis pathway. Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.<ref>PMID:14694473</ref> <ref>PMID:15218104</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Actinoalloteichus caeruleus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Freel Meyers CL]] | ||
[[Category: | [[Category: Gomez Garcia I]] | ||
[[Category: | [[Category: Lawson DM]] | ||
[[Category: Stevenson | [[Category: Stevenson CEM]] | ||
[[Category: Uson | [[Category: Uson I]] | ||
[[Category: Walsh | [[Category: Walsh CT]] | ||
