2b68: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Solution structure of the recombinant Crassostrea gigas defensin== | ==Solution structure of the recombinant Crassostrea gigas defensin== | ||
<StructureSection load='2b68' size='340' side='right'caption='[[2b68 | <StructureSection load='2b68' size='340' side='right'caption='[[2b68]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2b68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2b68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Crassostrea_gigas Crassostrea gigas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B68 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b68 OCA], [https://pdbe.org/2b68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b68 RCSB], [https://www.ebi.ac.uk/pdbsum/2b68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b68 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b68 OCA], [https://pdbe.org/2b68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b68 RCSB], [https://www.ebi.ac.uk/pdbsum/2b68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b68 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DEFCG_CRAGI DEFCG_CRAGI] Antibacterial peptide mostly active against Gram-positive bacteria (M.lysodeikticus, S.aureus, and the marine bacteria, B.stationis, and M.maritypicum) (PubMed:16246846). It acts by selectively inhibiting peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:20605792). It does not disrupt cell membranes (PubMed:20605792). Is noticeably more potent than Cg-Defh1 (PubMed:20605792). It shows no or limited activities against Gram-negative bacteria and filamentous fungi (PubMed:16246846).<ref>PMID:16246846</ref> <ref>PMID:20605792</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Crassostrea gigas]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Amaury | [[Category: Amaury H]] | ||
[[Category: Aumelas | [[Category: Aumelas A]] | ||
[[Category: Bachere | [[Category: Bachere E]] | ||
[[Category: Bulet | [[Category: Bulet P]] | ||
[[Category: Escoubas | [[Category: Escoubas JM]] | ||
[[Category: Favrel | [[Category: Favrel P]] | ||
[[Category: Fievet | [[Category: Fievet J]] | ||
[[Category: Garnier | [[Category: Garnier J]] | ||
[[Category: Gonzales | [[Category: Gonzales M]] | ||
[[Category: Gueguen | [[Category: Gueguen Y]] | ||
[[Category: Lelong | [[Category: Lelong C]] | ||
