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==Plla lectin, trisaccharide complex==
==Plla lectin, trisaccharide complex==
<StructureSection load='5ofx' size='340' side='right' caption='[[5ofx]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5ofx' size='340' side='right'caption='[[5ofx]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ofx]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Pholl Pholl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OFX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OFX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ofx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Photorhabdus_laumondii_subsp._laumondii_TTO1 Photorhabdus laumondii subsp. laumondii TTO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OFX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=RAF:RAFFINOSE'>RAF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">plu2096 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243265 PHOLL])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900002:raffinose'>PRD_900002</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ofx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ofx OCA], [http://pdbe.org/5ofx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ofx RCSB], [http://www.ebi.ac.uk/pdbsum/5ofx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ofx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ofx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ofx OCA], [https://pdbe.org/5ofx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ofx RCSB], [https://www.ebi.ac.uk/pdbsum/5ofx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ofx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLLA_PHOLL PLLA_PHOLL] Lectin that specifically binds alpha-galactoside-terminating glycoconjugates. Shows high apparent binding to the alpha-Gal epitope (Gal-alpha-1,3-Gal-beta-1,4-GlcNAc terminating glycans) as well as to Gal-alpha-1,4-GlcNAc and Gal-alpha-1,3-GalNAc. Gal-alpha-1,3-GalNAc may be one natural ligand bound by PllA both in the nematode symbiont and in infected insects.<ref>PMID:28972138</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pholl]]
[[Category: Large Structures]]
[[Category: Koehnke, J]]
[[Category: Photorhabdus laumondii subsp. laumondii TTO1]]
[[Category: Sikandar, A]]
[[Category: Koehnke J]]
[[Category: Carbohydrate]]
[[Category: Sikandar A]]
[[Category: Complex]]
[[Category: Lectin]]
[[Category: Plla]]
[[Category: Sugar binding protein]]
Retrieved from "https://proteopedia.org/5ofx"