Amiodarone: Difference between revisions
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Amiodarone is categorized as a class III antiarrhythmic agent, and prolongs phase 3 of the cardiac action potential, the repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. It has numerous other effects, however, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. | Amiodarone is categorized as a class III antiarrhythmic agent, and prolongs phase 3 of the cardiac action potential, the repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. It has numerous other effects, however, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. | ||
Amiodarone is a blocker of [[Potassium Channel|voltage gated potassium (KCNH2) | Amiodarone is a blocker of [[Potassium Channel|voltage gated potassium]] (more exactly KCNH2) and voltage gated calcium channels (CACNA2D2).<ref name="a50">[https://go.drugbank.com/drugs/DB01118 "Amiodarone".] Drugbank. Retrieved 28 May 2019.</ref> | ||
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Revision as of 13:35, 18 December 2023
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