8k9t: Difference between revisions
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==Cryo-EM structure of the products-bound PGAP1(Bst1)-S327A from Chaetonium thermophilum== | |||
<StructureSection load='8k9t' size='340' side='right'caption='[[8k9t]], [[Resolution|resolution]] 2.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8k9t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Psychromonas_sp._B3M02 Psychromonas sp. B3M02] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K9T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.66Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=05E:2-azanylethyl+[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl]+hydrogen+phosphate'>05E</scene>, <scene name='pdbligand=80Y:2-azanylethyl+[(2R,3S,4S,5S,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl+hydrogen+phosphate'>80Y</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=LYI:[(2~{R})-1-octadecoxy-3-[oxidanyl-[(2~{R},3~{R},5~{S},6~{R})-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl]+(5~{Z},8~{Z},11~{Z},14~{Z})-icosa-5,8,11,14-tetraenoate'>LYI</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=PA1:2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSE'>PA1</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k9t OCA], [https://pdbe.org/8k9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k9t RCSB], [https://www.ebi.ac.uk/pdbsum/8k9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k9t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A366VY15_9GAMM A0A366VY15_9GAMM] [https://www.uniprot.org/uniprot/G0S652_CHATD G0S652_CHATD] Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.[ARBA:ARBA00003496][RuleBase:RU365011] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Psychromonas sp. B3M02]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Hong J]] | |||
[[Category: Li D]] | |||
[[Category: Li T]] | |||
[[Category: Qu Q]] | |||
Revision as of 10:03, 20 December 2023
Cryo-EM structure of the products-bound PGAP1(Bst1)-S327A from Chaetonium thermophilum
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