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'''Unreleased structure'''


The entry 8ppv is ON HOLD  until Paper Publication
==Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches==
 
<StructureSection load='8ppv' size='340' side='right'caption='[[8ppv]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
Authors: Betancurt-Anzola, L., Martinez-Carranza, M., Zatopek, K.M., Gardner, A.F., Sauguet, L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ppv]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PPV FirstGlance]. <br>
Description: Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C7R:2-DEOXY-5-O-THIOPHOSPHONOCYTIDINE'>C7R</scene>, <scene name='pdbligand=GS:GUANOSINE-5-THIO-MONOPHOSPHATE'>GS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PST:THYMIDINE-5-THIOPHOSPHATE'>PST</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Zatopek, K.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ppv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ppv OCA], [https://pdbe.org/8ppv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ppv RCSB], [https://www.ebi.ac.uk/pdbsum/8ppv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ppv ProSAT]</span></td></tr>
[[Category: Betancurt-Anzola, L]]
</table>
[[Category: Martinez-Carranza, M]]
== Function ==
[[Category: Gardner, A.F]]
[https://www.uniprot.org/uniprot/PCNA_PYRAB PCNA_PYRAB] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non-specific cleavage.[HAMAP-Rule:MF_00317]<ref>PMID:22431731</ref>
[[Category: Sauguet, L]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus abyssi GE5]]
[[Category: Betancurt-Anzola L]]
[[Category: Gardner AF]]
[[Category: Martinez-Carranza M]]
[[Category: Sauguet L]]
[[Category: Zatopek KM]]
Retrieved from "https://proteopedia.org/8ppv"