2x6a: Difference between revisions
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<StructureSection load='2x6a' size='340' side='right'caption='[[2x6a]], [[Resolution|resolution]] 3.10Å' scene=''> | <StructureSection load='2x6a' size='340' side='right'caption='[[2x6a]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2x6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6A FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6a OCA], [https://pdbe.org/2x6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6a RCSB], [https://www.ebi.ac.uk/pdbsum/2x6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6a ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6a OCA], [https://pdbe.org/2x6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6a RCSB], [https://www.ebi.ac.uk/pdbsum/2x6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Magnetospirillum magnetotacticum]] | ||
[[Category: | [[Category: Caputo AT]] | ||
[[Category: | [[Category: Clarke OB]] | ||
[[Category: | [[Category: Gulbis JM]] | ||
[[Category: | [[Category: Hill AP]] | ||
[[Category: | [[Category: Smith BJ]] | ||
[[Category: | [[Category: Vandenberg JI]] | ||
