2xce: Difference between revisions
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<StructureSection load='2xce' size='340' side='right'caption='[[2xce]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='2xce' size='340' side='right'caption='[[2xce]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xce]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2xce]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XCE FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xce OCA], [https://pdbe.org/2xce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xce RCSB], [https://www.ebi.ac.uk/pdbsum/2xce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xce ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xce OCA], [https://pdbe.org/2xce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xce RCSB], [https://www.ebi.ac.uk/pdbsum/2xce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xce ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/YNCF_BACSU YNCF_BACSU] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bacillus subtilis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Burchell L]] | |||
[[Category: Burchell | [[Category: Fogg M]] | ||
[[Category: Fogg | [[Category: Garcia-Nafria J]] | ||
[[Category: Garcia-Nafria | [[Category: Rzechorzek N]] | ||
[[Category: Rzechorzek | [[Category: Takezawa M]] | ||
[[Category: Takezawa | [[Category: Wilson KS]] | ||
[[Category: Wilson | |||