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<StructureSection load='2xdr' size='340' side='right'caption='[[2xdr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2xdr' size='340' side='right'caption='[[2xdr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xdr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XDR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xdr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XDR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.301&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wme|2wme]], [[2wox|2wox]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xdr OCA], [https://pdbe.org/2xdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xdr RCSB], [https://www.ebi.ac.uk/pdbsum/2xdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xdr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xdr OCA], [https://pdbe.org/2xdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xdr RCSB], [https://www.ebi.ac.uk/pdbsum/2xdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xdr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/BETB_PSEAE BETB_PSEAE]] Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.<ref>PMID:21732915</ref>
[https://www.uniprot.org/uniprot/BETB_PSEAE BETB_PSEAE] Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.<ref>PMID:21732915</ref>  


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Betaine-aldehyde dehydrogenase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Diaz-Sanchez, A G]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Gonzalez-Segura, L]]
[[Category: Diaz-Sanchez AG]]
[[Category: Lira-Rocha, A]]
[[Category: Gonzalez-Segura L]]
[[Category: Munoz-Clares, R A]]
[[Category: Lira-Rocha A]]
[[Category: Rudino-Pinera, E]]
[[Category: Munoz-Clares RA]]
[[Category: Aldehyde oxidation]]
[[Category: Rudino-Pinera E]]
[[Category: Nadph complex]]
[[Category: Oxidoreductase]]

Latest revision as of 10:29, 20 December 2023

CRYSTALLOGRAPHIC STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE MUTANT E252A FROM PSEUDOMONAS AERUGINOSA

2xdr, resolution 2.30Å

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