2xec: Difference between revisions
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<StructureSection load='2xec' size='340' side='right'caption='[[2xec]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2xec' size='340' side='right'caption='[[2xec]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xec]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2xec]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nocardia_farcinica_IFM_10152 Nocardia farcinica IFM 10152]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xec OCA], [https://pdbe.org/2xec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xec RCSB], [https://www.ebi.ac.uk/pdbsum/2xec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xec ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xec OCA], [https://pdbe.org/2xec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xec RCSB], [https://www.ebi.ac.uk/pdbsum/2xec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xec ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MAIA_NOCFA MAIA_NOCFA] Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. Shows a strict specificity for maleate, with no activity detected toward structurally related substrates including citraconate, mesaconate, dimethylmaleate, and maleamide.<ref>PMID:20677745</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Nocardia farcinica IFM 10152]] | ||
[[Category: Baudendistel N]] | |||
[[Category: Baudendistel | [[Category: Bruce NC]] | ||
[[Category: Bruce | [[Category: Fisch F]] | ||
[[Category: Fisch | [[Category: Grogan G]] | ||
[[Category: Grogan | [[Category: Hart S]] | ||
[[Category: Hart | [[Category: Hauer B]] | ||
[[Category: Hauer | [[Category: Martinez-Fleites C]] | ||
[[Category: Martinez-Fleites | [[Category: Turkenburg JP]] | ||
[[Category: Turkenburg | |||
