4bdo: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='4bdo' size='340' side='right'caption='[[4bdo]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='4bdo' size='340' side='right'caption='[[4bdo]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bdo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BDO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bdo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BDO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=KAI:3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE'>KAI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1s50|1s50]], [[1s7y|1s7y]], [[1s9t|1s9t]], [[1sd3|1sd3]], [[1tt1|1tt1]], [[1yae|1yae]], [[2i0b|2i0b]], [[2i0c|2i0c]], [[2xxr|2xxr]], [[2xxt|2xxt]], [[2xxu|2xxu]], [[2xxv|2xxv]], [[2xxw|2xxw]], [[2xxx|2xxx]], [[2xxy|2xxy]], [[4bdl|4bdl]], [[4bdm|4bdm]], [[4bdn|4bdn]], [[4bdq|4bdq]], [[4bdr|4bdr]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=KAI:3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE'>KAI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bdo OCA], [https://pdbe.org/4bdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bdo RCSB], [https://www.ebi.ac.uk/pdbsum/4bdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bdo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bdo OCA], [https://pdbe.org/4bdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bdo RCSB], [https://www.ebi.ac.uk/pdbsum/4bdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bdo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GRIK2_RAT GRIK2_RAT]] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).<ref>PMID:17486098</ref> <ref>PMID:17115050</ref>
[https://www.uniprot.org/uniprot/GRIK2_RAT GRIK2_RAT] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).<ref>PMID:17486098</ref> <ref>PMID:17115050</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Green, T]]
[[Category: Rattus norvegicus]]
[[Category: Mayans, O]]
[[Category: Green T]]
[[Category: Nayeem, N]]
[[Category: Mayans O]]
[[Category: Ionotropic glutamate receptor]]
[[Category: Nayeem N]]
[[Category: Kainate receptor]]
[[Category: Metal transport]]
Retrieved from "https://proteopedia.org/4bdo"