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==Solution structure of the Murine BAG domain of Bcl2-associated athanogene 3==
==Solution structure of the Murine BAG domain of Bcl2-associated athanogene 3==
<StructureSection load='1uk5' size='340' side='right'caption='[[1uk5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1uk5' size='340' side='right'caption='[[1uk5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UK5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UK5 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FANTOM 2 cDNA 4931440G06 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uk5 OCA], [https://pdbe.org/1uk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uk5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uk5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1uk5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uk5 OCA], [https://pdbe.org/1uk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uk5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uk5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1uk5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/BAG3_MOUSE BAG3_MOUSE]] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.  
[https://www.uniprot.org/uniprot/BAG3_MOUSE BAG3_MOUSE] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Hatta, R]]
[[Category: Hatta R]]
[[Category: Hayashi, F]]
[[Category: Hayashi F]]
[[Category: Structural genomic]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Yoshida M]]
[[Category: Yoshida, M]]
[[Category: Bi]]
[[Category: Cair-1]]
[[Category: Chaperone]]
[[Category: Rsgi]]
[[Category: Triple helix bandle]]
Retrieved from "https://proteopedia.org/1uk5"