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<StructureSection load='2cua' size='340' side='right'caption='[[2cua]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2cua' size='340' side='right'caption='[[2cua]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cua OCA], [https://pdbe.org/2cua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cua RCSB], [https://www.ebi.ac.uk/pdbsum/2cua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cua ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cua OCA], [https://pdbe.org/2cua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cua RCSB], [https://www.ebi.ac.uk/pdbsum/2cua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/COX2_THETH COX2_THETH]] Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).  
[https://www.uniprot.org/uniprot/COX2_THETH COX2_THETH] Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
[[Category: Cytochrome-c oxidase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bellamy, H]]
[[Category: Thermus thermophilus]]
[[Category: Blackburn, N J]]
[[Category: Bellamy H]]
[[Category: Fee, J A]]
[[Category: Blackburn NJ]]
[[Category: Mcree, D E]]
[[Category: Fee JA]]
[[Category: Sanders, D]]
[[Category: Mcree DE]]
[[Category: Stura, E A]]
[[Category: Sanders D]]
[[Category: Williams, P A]]
[[Category: Stura EA]]
[[Category: Cua center]]
[[Category: Williams PA]]
[[Category: Electron transport]]

Revision as of 00:07, 28 December 2023

THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS

2cua, resolution 1.60Å

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