5ovk: Difference between revisions

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<StructureSection load='5ovk' size='340' side='right'caption='[[5ovk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5ovk' size='340' side='right'caption='[[5ovk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ovk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OVK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5OVK FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ovk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OVK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ovk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ovk OCA], [http://pdbe.org/5ovk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ovk RCSB], [http://www.ebi.ac.uk/pdbsum/5ovk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ovk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ovk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ovk OCA], [https://pdbe.org/5ovk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ovk RCSB], [https://www.ebi.ac.uk/pdbsum/5ovk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ovk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FABG_MYCS2 FABG_MYCS2]] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.  
[https://www.uniprot.org/uniprot/MABA_MYCS2 MABA_MYCS2] Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis (By similarity). Catalyzes the NADPH-dependent reduction of beta-ketoacyl derivatives, the second step of the FAS-II elongation cycle (By similarity). Has a preference for longer substrates (PubMed:29717709). Can use CoA derivatives as substrates in vitro (PubMed:29717709).[UniProtKB:P9WGT3]<ref>PMID:29717709</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blaise, M]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Flipo, M]]
[[Category: Blaise M]]
[[Category: Kremer, L]]
[[Category: Flipo M]]
[[Category: Kussau, T]]
[[Category: Kremer L]]
[[Category: Olieric, V]]
[[Category: Kussau T]]
[[Category: Viljoen, A]]
[[Category: Olieric V]]
[[Category: Wyk, N Van]]
[[Category: Van Wyk N]]
[[Category: Beta-keto-acyl-acp-reductase]]
[[Category: Viljoen A]]
[[Category: Fabg]]
[[Category: Oxidoreductase]]
[[Category: Sdr]]
Retrieved from "https://proteopedia.org/5ovk"