DNA polymerase: Difference between revisions
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DNA polymerases are some of the most accurate enzymes and have about one mistake for every one billion copies. When a mistake is made, many of the DNA polymerases have the ability to proofread the newly synthesized DNA and correct any mistakes made during replication. The enzymes proofread in the 5'-3' direction. When an error is found, the misplaced nucleotide is cut out so the correct nucleotide can be inserted. This process is often referred to as '''5'-3'exonuclease activity'''. | DNA polymerases are some of the most accurate enzymes and have about one mistake for every one billion copies. When a mistake is made, many of the DNA polymerases have the ability to proofread the newly synthesized DNA and correct any mistakes made during replication. The enzymes proofread in the 5'-3' direction. When an error is found, the misplaced nucleotide is cut out so the correct nucleotide can be inserted. This process is often referred to as '''5'-3'exonuclease activity'''. | ||
==Disease== | |||
Viral DNA polymerase is inhibited by [[Aciclovir]] which is used for treatment of various viral infections. | |||
==Types of DNA Polymerase== | ==Types of DNA Polymerase== | ||
