3iyp: Difference between revisions

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<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/E7 E7], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref> 
[https://www.uniprot.org/uniprot/Q9QP24_9ENTO Q9QP24_9ENTO]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
[[Category: E7]]
[[Category: Echovirus E7]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human echovirus 7]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bator, C M]]
[[Category: Bator CM]]
[[Category: Bowman, V D]]
[[Category: Bowman VD]]
[[Category: Chipman, P R]]
[[Category: Chipman PR]]
[[Category: Cifuente, J O]]
[[Category: Cifuente JO]]
[[Category: Hafenstein, S]]
[[Category: Hafenstein S]]
[[Category: Harris, K G]]
[[Category: Harris KG]]
[[Category: Lin, F]]
[[Category: Lin F]]
[[Category: Medof, D E]]
[[Category: Medof DE]]
[[Category: Plevka, P]]
[[Category: Plevka P]]
[[Category: Rossmann, M G]]
[[Category: Rossmann MG]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: Complex]]
[[Category: Daf]]
[[Category: Echovirus]]
[[Category: Icosahedral virus]]
[[Category: Receptor]]
[[Category: Virus]]

Revision as of 11:32, 24 January 2024

The Interaction of Decay-accelerating Factor with Echovirus 7

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