6q83: Difference between revisions

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<StructureSection load='6q83' size='340' side='right'caption='[[6q83]], [[Resolution|resolution]] 4.53&Aring;' scene=''>
<StructureSection load='6q83' size='340' side='right'caption='[[6q83]], [[Resolution|resolution]] 4.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6q83]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q83 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q83 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6q83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Q83 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAP122, PDR6, YGL016W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.53&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q83 OCA], [http://pdbe.org/6q83 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q83 RCSB], [http://www.ebi.ac.uk/pdbsum/6q83 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q83 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6q83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q83 OCA], [https://pdbe.org/6q83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6q83 RCSB], [https://www.ebi.ac.uk/pdbsum/6q83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6q83 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KA122_YEAST KA122_YEAST]] Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm. Required for the nuclear import of the complex composed the large subunit (TOA1) and the small subunit (TOA2) of the general transcription factor IIA (TFIIA). Required for the nuclear import of the RNR2-RNR4 heterodimer, also called beta-beta' subunit, which corresponds to the small subunit of the ribonucleotide reductase (RNR). May play a role in regulation of pleiotropic drug resistance.<ref>PMID:10525531</ref> <ref>PMID:16432237</ref> <ref>PMID:1882553</ref> <ref>PMID:18838542</ref> [[http://www.uniprot.org/uniprot/UBC9_YEAST UBC9_YEAST]] E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).<ref>PMID:9341106</ref> <ref>PMID:11572779</ref> 
[https://www.uniprot.org/uniprot/KA122_YEAST KA122_YEAST] Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm. Required for the nuclear import of the complex composed the large subunit (TOA1) and the small subunit (TOA2) of the general transcription factor IIA (TFIIA). Required for the nuclear import of the RNR2-RNR4 heterodimer, also called beta-beta' subunit, which corresponds to the small subunit of the ribonucleotide reductase (RNR). May play a role in regulation of pleiotropic drug resistance.<ref>PMID:10525531</ref> <ref>PMID:16432237</ref> <ref>PMID:1882553</ref> <ref>PMID:18838542</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6q83" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6q83" style="background-color:#fffaf0;"></div>
==See Also==
*[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aksu, M]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Gorlich, D]]
[[Category: Aksu M]]
[[Category: Trakhanov, S]]
[[Category: Gorlich D]]
[[Category: Vera-Rodriguez, A]]
[[Category: Trakhanov S]]
[[Category: Biportin]]
[[Category: Vera-Rodriguez A]]
[[Category: Importin-beta family]]
[[Category: Nuclear import]]
[[Category: Protein transport]]
[[Category: Sumoylation]]
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