6qng: Difference between revisions

<table><tr><td colspan='2'>[[6qng]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QNG FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J95:~{N}-butyl-4-chloranyl-2-(cyclohexylamino)-5-sulfamoyl-benzamide'>J95</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qng OCA], [https://pdbe.org/6qng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qng RCSB], [https://www.ebi.ac.uk/pdbsum/6qng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qng ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CAH12_HUMAN CAH12_HUMAN] Defects in CA12 are the cause of hyperchlorhidrosis isolated (HCHLH) [MIM:[https://omim.org/entry/143860 143860]. HCHLH is a disorder characterized by excessive sweating and increased sweat chloride levels. Affected individuals suffer from episodes of hyponatremic dehydration and report increased amounts of visible salt precipitates in sweat.<ref>PMID:21035102</ref>  

[https://www.uniprot.org/uniprot/CAH12_HUMAN CAH12_HUMAN] Reversible hydration of carbon dioxide.

 

[[Category: Homo sapiens]]

[[Category: Dvinskis E]]

[[Category: Leitans J]]

[[Category: Tars K]]