6t2l: Difference between revisions

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<StructureSection load='6t2l' size='340' side='right'caption='[[6t2l]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
<StructureSection load='6t2l' size='340' side='right'caption='[[6t2l]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6t2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T2L FirstGlance]. <br>
<table><tr><td colspan='2'>[[6t2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T2L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HL9:5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide'>HL9</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HL9:5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide'>HL9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t2l OCA], [https://pdbe.org/6t2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t2l RCSB], [https://www.ebi.ac.uk/pdbsum/6t2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t2l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t2l OCA], [https://pdbe.org/6t2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t2l RCSB], [https://www.ebi.ac.uk/pdbsum/6t2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t2l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).  
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: As 4 1583]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hocker, B]]
[[Category: Streptomyces avidinii]]
[[Category: Lechner, H]]
[[Category: Hocker B]]
[[Category: Artificial cofactor]]
[[Category: Lechner H]]
[[Category: Biotin-binding protein]]
[[Category: Catalyst]]
[[Category: Streptavidin]]

Latest revision as of 12:53, 24 January 2024

Streptavidin variants harbouring an artificial organocatalyst based cofactor

6t2l, resolution 1.00Å

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