6tee: Difference between revisions

<table><tr><td colspan='2'>[[6tee]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TEE FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tee OCA], [https://pdbe.org/6tee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tee RCSB], [https://www.ebi.ac.uk/pdbsum/6tee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tee ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RUTA_ECOLI RUTA_ECOLI] Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. Requires the flavin reductase RutF to regenerate FMN in vivo. RutF can be substituted by Fre in vitro.<ref>PMID:16540542</ref> <ref>PMID:20400551</ref>  

[[Category: Escherichia coli K-12]]

[[Category: Matthews A]]

[[Category: Saleem-Batcha R]]

[[Category: Teufel R]]