6za4: Difference between revisions
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<StructureSection load='6za4' size='340' side='right'caption='[[6za4]], [[Resolution|resolution]] 2.09Å' scene=''> | <StructureSection load='6za4' size='340' side='right'caption='[[6za4]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6za4]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6za4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZA4 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.092Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=M83:5-(3-cyanophenyl)furan-2-carboxylic+acid'>M83</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6za4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6za4 OCA], [https://pdbe.org/6za4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6za4 RCSB], [https://www.ebi.ac.uk/pdbsum/6za4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6za4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Bellinzoni | [[Category: Bellinzoni M]] | ||
[[Category: Meneghetti | [[Category: Meneghetti F]] | ||
[[Category: Mori | [[Category: Mori M]] | ||
[[Category: Villa | [[Category: Villa S]] | ||